Monitoring heart involvement in treated and untreated transthyretin amyloidosis
Giulio Sinigiani, Paolo Milani, Laura De Michieli, Giuseppe Damiano Sanna, Stefano Perlini, Alberto Cipriani, Giovanni Palladini · 2025
Read Monitoring heart involvement in treated and untreated transthyretin amyloidosis by Giulio Sinigiani, Paolo Milani, Laura De Michieli, Giuseppe Damiano Sanna, Stefano Perlini, Alberto Cipriani, Giovanni Palladini (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12722399.txt.
Description
Giulio Sinigiani and co-authors review how to track heart disease in a protein deposit illness that slowly stiffens the heart, in work published in 2025. A stabilizing drug has proven survival benefit, yet many patients still worsen on it. Follow up today borrows tools from general heart failure care.
Clinics check symptoms, blood markers, scans, and walking capacity at intervals. Real world data show these tools can miss early decline in treated patients. Newer drugs make spotting weak response early more urgent, since switching in time may matter. The authors map what is known, name the gaps, and argue for a shared, simple monitoring framework that trials and clinics can both use.
Catalog record
| CREATOR | Giulio Sinigiani, Paolo Milani, Laura De Michieli, Giuseppe Damiano Sanna, Stefano Perlini, Alberto Cipriani, Giovanni Palladini |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 28 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |