Identification of diagnostic and prognostic biomarkers for tuberculosis based on plasma proteomics

Yan Hu, Chao Quan, Yuanyuan Zhou, Shangyan Liang, Xuan Wang, Jun Li, Wenqi Liu, Yuzhong Xu, Peng Liu · 2025

Read Identification of diagnostic and prognostic biomarkers for tuberculosis based on plasma proteomics by Yan Hu, Chao Quan, Yuanyuan Zhou, Shangyan Liang, Xuan Wang, Jun Li, Wenqi Liu, Yuzhong Xu, Peng Liu (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12721542.txt.

Description

Yan Hu and co-authors hunt blood protein markers for tuberculosis diagnosis and prognosis in a 2025 paper. Telling tuberculosis apart from a related lung infection, and active disease from latent infection, defeats current tests too often. Plasma protein patterns might separate the groups more cleanly.

The team profiled blood from five groups: active and latent tuberculosis, the related infection, cured patients, and healthy donors. More than a thousand proteins were measured. Well over one hundred differed across the key comparisons, clustering in outer cell regions. Some tied to inflammation and surface barrier roles, offering candidate markers for stage and treatment response.

Catalog record

CREATORYan Hu, Chao Quan, Yuanyuan Zhou, Shangyan Liang, Xuan Wang, Jun Li, Wenqi Liu, Yuzhong Xu, Peng Liu
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE44 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12721542

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