Glue ablation therapy for patients with great saphenous vein varicosities: A randomized, parallel-controlled, multicenter, non-inferiority trial

Kangkang Zhi, Sili Zou, Yi Hong, Lianrui Guo, Yixia Qi, Lei Zhang, Junlu Peng, Bo Ye, Guofu Zheng, Bin Hao, Huimin Xu, Bin Chen, Yifeng Pan, Yuefeng Zhu, Jinjin Wu, Xiaojin Huang, Shenci Wen, Xiang Wang, Lefeng Qu · 2025

Read Glue ablation therapy for patients with great saphenous vein varicosities: A randomized, parallel-controlled, multicenter, non-inferiority trial by Kangkang Zhi, Sili Zou, Yi Hong, Lianrui Guo, Yixia Qi, Lei Zhang, Junlu Peng, Bo Ye, Guofu Zheng, Bin Hao, Huimin Xu, Bin Chen, Yifeng Pan, Yuefeng Zhu, Jinjin Wu, Xiaojin Huang, Shenci Wen, Xiang Wang, Lefeng Qu (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12721361.txt.

Description

Kangkang Zhi and co-authors run a multicenter trial comparing glue ablation with radiofrequency ablation for varicose veins in the great saphenous vein. Care for varicose veins has moved from open surgery toward targeted, low-impact procedures, but long-term data on the glue method stay limited. The trial enrolls 177 patients across centers, with 89 assigned to glue and 88 to radio waves. Follow-up visits run from one week to twelve months after treatment.

The main test is whether the glue method closes the vein fully at three months at a rate not worse than the standard method. The team also tracks closure at twelve months, procedure time, pain, bruising, and two symptom scores. The glue group shows no device-related complications. Unlike the radio wave group, it needs no tumescent fluid injections. Early results support glue as a safe rival treatment.

Catalog record

CREATORKangkang Zhi, Sili Zou, Yi Hong, Lianrui Guo, Yixia Qi, Lei Zhang, Junlu Peng, Bo Ye, Guofu Zheng, Bin Hao, Huimin Xu, Bin Chen, Yifeng Pan, Yuefeng Zhu, Jinjin Wu, Xiaojin Huang, Shenci Wen, Xiang Wang, Lefeng Qu
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE31 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12721361

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