Analysis of a simple disk diffusion method to evaluate ceftazidime–avibactam/aztreonam combination synergism against New Delhi metallo-beta-lactamase-producing clinical isolates
Reena Rajan, Sasikala Gopinathan, A. V. Raghavendra Rao, Rajarajeswari B, Sureshkumar Mathavi · 2025
Read Analysis of a simple disk diffusion method to evaluate ceftazidime–avibactam/aztreonam combination synergism against New Delhi metallo-beta-lactamase-producing clinical isolates by Reena Rajan, Sasikala Gopinathan, A. V. Raghavendra Rao, Rajarajeswari B, Sureshkumar Mathavi (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12720981.txt.
Description
Reena Rajan and co-authors test a simple lab method for pairing two drugs against hardy bacteria in this 2025 study. Many hospital bacteria now resist standard drugs. A pair of drugs, ceftazidime-avibactam plus aztreonam, can work together against strains that make a potent enzyme.
The team used a plain disk method, a cheap test any lab can run. They worked with clinical samples that produce the New Delhi enzyme, a strong drug-breaking tool. They also hunted the genes behind drug resistance in the samples. The study checks whether a low-cost test can guide use of the drug pair.
Catalog record
| CREATOR | Reena Rajan, Sasikala Gopinathan, A. V. Raghavendra Rao, Rajarajeswari B, Sureshkumar Mathavi |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 30 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |