The Gut–Kidney Axis in Uric Acid Nephropathy: Microbiota, Metabolic Crosstalk, and Translational Prospects
Jiahao Liang, Yanzhi Qiu, Tong Fu, Jianing Li, Jiamin Yang, Ying Tong · 2025
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Description
Jiahao Liang and co-authors review the gut-kidney axis in uric acid kidney disease. Their twenty twenty-five review links high uric acid, inflammation, and a disturbed gut microbe mix. The gut and kidneys trade signals that shape urate handling and immune tone.
Microbe products, such as short-chain fatty acids and indoxyl sulfate, carry much of that crosstalk. Harm runs by crystal deposits and by crystal-free paths that scar kidney tubes. Treatments aimed at the gut are weighed: probiotics, synbiotics, postbiotics, and stool transplant among them. The review builds one frame for a tangled disease and flags where lab promise may turn clinical.
Catalog record
| CREATOR | Jiahao Liang, Yanzhi Qiu, Tong Fu, Jianing Li, Jiamin Yang, Ying Tong |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 64 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |