Unmasking the ‘rods and rings’ antinuclear antibody pattern: a sign of hepatitis C treatment and a risk factor for cerebrovascular disease

Ko-Ming Lin, Kuang-Hui Yu, Chao-Yang Hsiao, Yu-Jih Su, Tien-Ming Chan · 2025

Read Unmasking the ‘rods and rings’ antinuclear antibody pattern: a sign of hepatitis C treatment and a risk factor for cerebrovascular disease by Ko-Ming Lin, Kuang-Hui Yu, Chao-Yang Hsiao, Yu-Jih Su, Tien-Ming Chan (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12720668.txt.

Description

Ko-Ming Lin and co-authors investigate an unusual antibody pattern, nicknamed rods and rings, in blood tests from a large Taiwan hospital, in a 2025 study. The pattern is known to appear during hepatitis C treatment, especially with one drug, but its wider meaning is unclear. The team screened more than forty-three thousand samples and studied the thirty-five patients who showed the pattern.

Nearly nine in ten had hepatitis C, and most had taken the linked drug, with liver problems common. A few patients without the virus were taking beta-blocker heart drugs instead. Patients with very high antibody levels had more strokes and vessel disease than those with low levels. The authors urge more study of this possible warning sign.

Catalog record

CREATORKo-Ming Lin, Kuang-Hui Yu, Chao-Yang Hsiao, Yu-Jih Su, Tien-Ming Chan
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE27 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12720668

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