Research progress on histone deacetylases in peritoneal dialysis-associated peritoneal fibrosis
Wenhui Qiu, Jiayi Chen, Tapas Ranjan Behera, Ying Huang, Chenling Chu, Baihui Xu, Quanquan Shen, Jingwen Yan · 2025
Read Research progress on histone deacetylases in peritoneal dialysis-associated peritoneal fibrosis by Wenhui Qiu, Jiayi Chen, Tapas Ranjan Behera, Ying Huang, Chenling Chu, Baihui Xu, Quanquan Shen, Jingwen Yan (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12720667.txt.
Description
Wenhui Qiu and co-authors review research on histone deacetylases, enzymes that steer gene activity, in the peritoneal fibrosis that can follow long-term peritoneal dialysis. This scarring of the belly lining can end dialysis by blocking fluid exchange. Most fibrosis work targets liver and kidney, leaving the peritoneum understudied.
The review covers how these enzymes and their inhibitors affect inflammation and scarring in the peritoneum. It sets out the enzymes' traits, their links with the extracellular matrix, and their part in whether fibrosis can roll back. Future study paths toward treatments are also weighed. The authors aim to give the field a firmer base for finding anti-fibrotic targets.
Catalog record
| CREATOR | Wenhui Qiu, Jiayi Chen, Tapas Ranjan Behera, Ying Huang, Chenling Chu, Baihui Xu, Quanquan Shen, Jingwen Yan |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 58 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |