Posterior fossa arachnoid cysts in multiple system atrophy
Audrey M Blazek Ramsay, Eoin P Flanagan, Elizabeth A Coon, Lauren M Jackson · 2025
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Description
Two rare conditions turning up in the same patient invites a question: shared cause, or pure chance? The authors describe three patients who carry fluid-filled arachnoid cysts in the back of the skull. All three later develop multiple system atrophy, a degenerative disease marked by failing movement and automatic body functions. The patients, aged 45 to 67 at presentation, each report two to three years of worsening symptoms. All show cerebellar signs plus features like blood pressure drops on standing and dream enactment during sleep.
Scans show the cysts together with the shrinkage of the pons and cerebellum that fits the disease. A rough probability calculation puts the chance overlap near one in a million. The authors judge coincidence the likelier story, while allowing that a space-taking cyst could still speed decline once present. They present the cases as a caution against reading deep meaning into rare pairings.
Catalog record
| CREATOR | Audrey M Blazek Ramsay, Eoin P Flanagan, Elizabeth A Coon, Lauren M Jackson |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 12 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |