Impact of the resumption of proactive recommendation of HPV vaccination on HPV vaccination rates in Japan: an interrupted time series analysis based on the VENUS study
Mahiro Sazawa, Chieko Ishiguro, Wataru Mimura, Megumi Maeda, Fumiko Murata, Haruhisa Fukuda · 2025
Read Impact of the resumption of proactive recommendation of HPV vaccination on HPV vaccination rates in Japan: an interrupted time series analysis based on the VENUS study by Mahiro Sazawa, Chieko Ishiguro, Wataru Mimura, Megumi Maeda, Fumiko Murata, Haruhisa Fukuda (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12718567.txt.
Description
Mahiro Sazawa and co-authors measured what happened when Japan restarted active promotion of the HPV vaccine in a 2025 study. Japan had paused its recommendation for eight years, and coverage fell below one percent, among the lowest in the world. In April 2022 the government resumed promotion and added a catch-up program.
Using registry data from one municipality, the team tracked vaccination across girls born from 2003 to 2011. The 2006 cohort reached the highest coverage by mid 2023, about one third for the first dose. A time series model showed first-dose rates jumped by about half right when promotion resumed. The trend after the jump stayed nearly flat. The study offers rare hard evidence that government recommendation itself drives vaccine uptake.
Catalog record
| CREATOR | Mahiro Sazawa, Chieko Ishiguro, Wataru Mimura, Megumi Maeda, Fumiko Murata, Haruhisa Fukuda |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 34 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |