Antipsychotic load during olanzapine mono- versus polytherapy and in relation to age
Vigdis Solhaug, Ragnhild Birkeland Waade, Lene Jansrud, Espen Molden, Elisabet Størset, Gudrun Høiseth, Marit Tveito · 2025
Read Antipsychotic load during olanzapine mono- versus polytherapy and in relation to age by Vigdis Solhaug, Ragnhild Birkeland Waade, Lene Jansrud, Espen Molden, Elisabet Størset, Gudrun Høiseth, Marit Tveito (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12718314.txt.
Description
Vigdis Solhaug and six co-authors measure total drug load in patients on olanzapine in a 2025 paper. Olanzapine is a drug for psychotic disorders, best used on its own. In real care, many patients get it with other like drugs. The team asked how total load differs between single and mixed use.
They used a drug monitoring service with 10,190 patients in total. Most, 86 percent, took olanzapine alone, while 14 percent took it with other drugs. The mixed group had about twice the drug load by dose and by blood level. Older patients got lower doses but kept near-equal blood levels. The authors warn that mixed use can quietly double exposure.
Catalog record
| CREATOR | Vigdis Solhaug, Ragnhild Birkeland Waade, Lene Jansrud, Espen Molden, Elisabet Størset, Gudrun Høiseth, Marit Tveito |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 30 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |