Combating Multidrug-Resistant Acinetobacter baumannii: Insights from Japan, with Global Relevance
Yusuke Yoshino, Yoshitaka Kimura, Fuyu Ito · 2025
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Description
Yusuke Yoshino and co-authors review a drug-resistant hospital germ in a 2025 paper, drawing lessons from Japan for the world. The germ, Acinetobacter baumannii, survives long on surfaces, gains drug resistance fast, and sparks outbreaks with ease. Global health authorities rank it in the highest critical tier of priority pathogens.
The review covers how resistance is defined, how it arises, and how the germ spreads in Japan and abroad. Carbapenem resistance flows mostly from OXA-type enzymes, often paired with backup mechanisms. Japan's isolates still respond to key drugs more often than those in many Asia-Pacific and Latin American settings. No single drug regimen wins everywhere, so paired drugs are common. The authors argue that gaps in resistance reflect gaps in surveillance, hygiene, and drug stewardship.
Catalog record
| CREATOR | Yusuke Yoshino, Yoshitaka Kimura, Fuyu Ito |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 37 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |