Glucagon‐Like Peptide‐2 (GLP‐2) Analogues in Patients With Short Bowel Syndrome Dependent on Parenteral Support: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials
Arsalan Hyder, Ankit Alria, Adnan Rafiq, Muhammad Faiq Akram, Talha Hassan, Eshah Fatima Ali, Farheen Vhora, Shajia Khan, Shah Gul Zahra, Muhammad Arslan Niazi, Uzair Jafar, Huzaifa Ahmad Cheema, Asma'a Munasar Ali Alsubari, Faryal Altaf, Adnan Bhat, Essam Rashad, Prasun Kumar Jalal · 2025
Read Glucagon‐Like Peptide‐2 (GLP‐2) Analogues in Patients With Short Bowel Syndrome Dependent on Parenteral Support: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials by Arsalan Hyder, Ankit Alria, Adnan Rafiq, Muhammad Faiq Akram, Talha Hassan, Eshah Fatima Ali, Farheen Vhora, Shajia Khan, Shah Gul Zahra, Muhammad Arslan Niazi, Uzair Jafar, Huzaifa Ahmad Cheema, Asma'a Munasar Ali Alsubari, Faryal Altaf, Adnan Bhat, Essam Rashad, Prasun Kumar Jalal (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12717787.txt.
Description
Arsalan Hyder and co-authors pool trials of gut hormone copies for short bowel syndrome in a 2025 review. When too little intestine remains, patients depend on intravenous feeding, which carries serious risks over time. Copies of the hormone GLP-2 help the gut adapt and absorb more.
Six randomized trials with 454 patients compared the drugs with placebo. Patients on treatment needed about 250 milliliters less intravenous feed per day. They were also roughly twice as likely to count as responders. Rates of side effects, including serious ones, matched the placebo groups. The authors back the drugs as effective, while noting the evidence base is still small.
Catalog record
| CREATOR | Arsalan Hyder, Ankit Alria, Adnan Rafiq, Muhammad Faiq Akram, Talha Hassan, Eshah Fatima Ali, Farheen Vhora, Shajia Khan, Shah Gul Zahra, Muhammad Arslan Niazi, Uzair Jafar, Huzaifa Ahmad Cheema, Asma'a Munasar Ali Alsubari, Faryal Altaf, Adnan Bhat, Essam Rashad, Prasun Kumar Jalal |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 25 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |