Association of hemoglobin glycation index with the severity and mortality of cardiovascular-kidney-metabolic syndrome: a population-based cohort study
Leiluo Geng, Xue Diao, Hong-jie Yu, Aimin Xu · 2025
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Description
Leiluo Geng and co-authors study a simple blood marker, the hemoglobin glycation index, in a combined heart, kidney, and metabolic syndrome that runs from stage 0 to stage 4. The index captures how much a person's glycated hemoglobin differs from what their blood sugar predicts. Using survey data on more than fourteen thousand American adults, the team linked the index to syndrome stage and to deaths over a median of seven and a half years.
A higher index went with a more advanced syndrome stage. Death risk followed a U shape: it fell as the index rose toward a middle point, then climbed beyond it, in both early and late stages. For heart-related deaths, the link was a straight rising line in the most advanced stage only. The authors propose the index as a cheap marker for judging risk in this syndrome, while noting the pattern changes with stage.
Catalog record
| CREATOR | Leiluo Geng, Xue Diao, Hong-jie Yu, Aimin Xu |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 54 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |