Risk Factors and Molecular Epidemiology of Infections Among Patients with Intestinal Colonization by Carbapenem-Resistant Enterobacteriaceae: A Retrospective Study of Active Screening in a Tertiary Hospital

Xinyue Li, Meijia Huang, Bin Shan, Xiaoyan Zhu, Yunmin Xu, Shaoxuan Li, Xundie Li, Xinyi Zheng, Yuehong Dong, Hongjuan Zhang · 2025

Read Risk Factors and Molecular Epidemiology of Infections Among Patients with Intestinal Colonization by Carbapenem-Resistant Enterobacteriaceae: A Retrospective Study of Active Screening in a Tertiary Hospital by Xinyue Li, Meijia Huang, Bin Shan, Xiaoyan Zhu, Yunmin Xu, Shaoxuan Li, Xundie Li, Xinyi Zheng, Yuehong Dong, Hongjuan Zhang (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12717027.txt.

Description

Li and co-authors study patients whose guts carry carbapenem-resistant bacteria, germs that shrug off some of the strongest antibiotics. These patients may stay well, or the same germs may later cause a real infection. The team wanted to know how often that happens and what raises the risk.

Screening 8,088 patients at a large Chinese hospital found only about half a percent carried the bacteria. Yet over a third of carriers later developed infection, mostly with Klebsiella pneumoniae in the lungs, blood, or urinary tract. The infecting strains nearly always matched the gut strains and carried the same resistance gene. Having several other illnesses raised the risk.

Catalog record

CREATORXinyue Li, Meijia Huang, Bin Shan, Xiaoyan Zhu, Yunmin Xu, Shaoxuan Li, Xundie Li, Xinyi Zheng, Yuehong Dong, Hongjuan Zhang
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE38 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12717027

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