Blood biomarkers of seizures in epilepsy: machine learning reveals altered plasma proteome
Sarah Akel, Saman Hosseini Ashtiani, Mayuresh Anant Sarangdhar, Markus Axelsson, Johan Zelano · 2025
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Description
Sarah Akel and co-authors hunt blood markers of recent seizures in a 2025 study. Epilepsy care lacks fluid tests that show seizure activity. Blood from adults with recent seizures was compared with seizure free patients. A broad protein panel measured well over a thousand proteins per sample.
Learning models and standard tests agreed on a set of differing proteins. A nerve fiber marker and several immune signals stood out. Groups of the flagged proteins clustered around inflammation paths. The profile points to immune shifts as a seizure companion worth tracking.
Catalog record
| CREATOR | Sarah Akel, Saman Hosseini Ashtiani, Mayuresh Anant Sarangdhar, Markus Axelsson, Johan Zelano |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 40 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |