Bond-Centric Modifications of Hyaluronic Acid: Synthesis, Processing, and Biomedical Applications
Anqi Yang, Pu Yang, Naisi Shen, Rui Wu, Xiangjun Liu, Yikun Ju, Lanjie Lei, Bairong Fang · 2025
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Description
Anqi Yang and seven co-authors review how chemists modify hyaluronic acid, a natural sugar found in human connective tissue, for medical use. The material is body friendly and breaks down safely, but plain versions have limits that spur redesign. The review sorts methods by the chemical bonds they form.
Physical mixing, chemical change, and crosslinking each tune how fast the material degrades, how strong it is, and how it responds to its surroundings. Uses span eye care, joint treatment, beauty medicine, wound healing, and drug delivery. The authors distill design rules linking bond choice to performance and safety. They close with challenges blocking wider clinical use.
Catalog record
| CREATOR | Anqi Yang, Pu Yang, Naisi Shen, Rui Wu, Xiangjun Liu, Yikun Ju, Lanjie Lei, Bairong Fang |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 162 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |