Association between triglyceride-glucose index combined with a body shape index and atherosclerotic cardiovascular disease risk varies by glycemic status: insights from the UK Biobank
Xinyi Shao, Zhaofu Tan, Lifu Sun, Yidian Fu, Aijun Chen, Jin Chen, Genlong Bai, Jingbo Zhang · 2025
Read Association between triglyceride-glucose index combined with a body shape index and atherosclerotic cardiovascular disease risk varies by glycemic status: insights from the UK Biobank by Xinyi Shao, Zhaofu Tan, Lifu Sun, Yidian Fu, Aijun Chen, Jin Chen, Genlong Bai, Jingbo Zhang (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12715960.txt.
Description
Xinyi Shao and co-authors study a combined risk index for heart and vessel disease in a 2025 paper. The index joins a blood-based insulin resistance score with a body shape measure. The team asked whether the combined score predicts disease differently depending on a person's blood sugar status.
Data came from the UK Biobank, split into normal sugar, pre-diabetes, and diabetes groups, and followed for about 15 years. Nearly 30,000 disease events occurred. Higher index values meant higher risk in the normal and diabetes groups, but no clear link appeared in the pre-diabetes group. The combined index beat its parts and rival combined scores at prediction. Part of its effect ran through white blood cell counts, a sign of inflammation.
Catalog record
| CREATOR | Xinyi Shao, Zhaofu Tan, Lifu Sun, Yidian Fu, Aijun Chen, Jin Chen, Genlong Bai, Jingbo Zhang |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 47 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |