Zmynd10 drives centriole biogenesis and multiciliogenesis through the transcriptional regulation of E2f4
Zhiming Liu, Qin Wu, Zhenhai Zhou, Wen Tan, Junlong Zhong, Shuai Fan, Kai Cao, Lu Huang · 2025
Read Zmynd10 drives centriole biogenesis and multiciliogenesis through the transcriptional regulation of E2f4 by Zhiming Liu, Qin Wu, Zhenhai Zhou, Wen Tan, Junlong Zhong, Shuai Fan, Kai Cao, Lu Huang (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12715256.txt.
Description
Zhiming Liu and seven co-authors find that a gene known for hair build in cells also drives the birth of many cilia. Their study appeared in twenty twenty-five. Cells with many cilia move fluid in the brain, clear mucus, and haul eggs, so their birth must be well run. The gene, Zmynd10, was known as a part builder for cilia arms.
When the gene was curbed in mouse brain cells, cilia thinned out a lot. Two linked genes fell too, and curbing one of them cut cilia in the same way. Gene checks showed the first gene turns the second on at its start switch. The chain gives a fresh view of how many-cilia cells form.
Catalog record
| CREATOR | Zhiming Liu, Qin Wu, Zhenhai Zhou, Wen Tan, Junlong Zhong, Shuai Fan, Kai Cao, Lu Huang |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 32 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |