Gut Microbiota and Atherosclerosis: Integrative Multi-Omics and Mechanistic Insights
Jiahuan Helen He, Hanwen Wang, Eric Qiu, Qibin Qi, Zheng Wang · 2025
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Description
Jiahuan Helen He and co-authors review how gut microbes join the slow clogging of arteries, in a 2025 paper. Atherosclerosis builds fatty plaques in vessel walls, and gut bacteria — through the chemicals they release — increasingly look like accomplices. Single studies disagree, so the review fuses three kinds of evidence: gene surveys of the gut community, chemical profiles, and protein data.
Across studies, pro-inflammatory species often bloomed in patients while helpful fiber-fermenting species thinned out. Microbe-made chemicals such as trimethylamine N-oxide tracked with disease, using carotid artery disease as the worked example. The combined picture points to gut targets — diet, microbes, or their chemicals — for future heart protection.
Catalog record
| CREATOR | Jiahuan Helen He, Hanwen Wang, Eric Qiu, Qibin Qi, Zheng Wang |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 64 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |