Early-Onset Parkinson’s Disease: Unique Features and Management Approaches
Jordan Hickman, Andrew Tsai, Michelle Fullard, Michael Korsmo, Emily Forbes, Sana Aslam, Alexander J. Baumgartner, Jeanne S. Feuerstein, Ece Bayram · 2025
Read Early-Onset Parkinson’s Disease: Unique Features and Management Approaches by Jordan Hickman, Andrew Tsai, Michelle Fullard, Michael Korsmo, Emily Forbes, Sana Aslam, Alexander J. Baumgartner, Jeanne S. Feuerstein, Ece Bayram (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12714827.txt.
Description
Jordan Hickman and co-authors review what makes early-onset Parkinson's disease distinct in a 2025 paper. Onset between twenty-one and fifty brings a different illness than the late-life form: slower motor decline, less dementia, but more involuntary movements and more missed diagnoses.
Single-gene causes appear far more often in young patients. Twisted postures, depression, and anxiety also run higher. Treatment tangles with careers and pregnancy, and drug side effects arrive earlier and harder. Most research still targets the late-onset disease. The authors call for trials and care models built around younger patients' longer horizon and different stakes.
Catalog record
| CREATOR | Jordan Hickman, Andrew Tsai, Michelle Fullard, Michael Korsmo, Emily Forbes, Sana Aslam, Alexander J. Baumgartner, Jeanne S. Feuerstein, Ece Bayram |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 39 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |