Nanogels with volume phase transition for biomedical applications
Zheng Li, Xiangliang Yang, Zifu Li · 2025
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Description
Zheng Li, Xiangliang Yang, and Zifu Li review in 2025 tiny gel particles that swell or shrink with their surroundings, and their uses in medicine. The gels are networks held by chemical links and by hydrogen bonds. At a set temperature they pass through a sharp change of volume.
The review explains how that change can be tuned in its position, sharpness, and range. Choices of building blocks, partners, links, shape, and even heavy water shift the switch point. Two uses lead the field: blocking blood vessels to starve tumors, and carrying drugs to tumors. Odd dips in gel traits near the switch point may themselves aid treatment. Tuned gels could one day release a drug only where the body is warm or acidic.
Catalog record
| CREATOR | Zheng Li, Xiangliang Yang, Zifu Li |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 44 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |