Decoding the Crosstalk Between Heat Shock Proteins and Phytochemicals in Thyroid Nodule Regression: Mechanisms and Therapeutic Implications
Ruina Zhang, Juanqin Lv · 2025
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Description
Ruina Zhang and Juanqin Lv review how plant compounds interact with heat shock proteins to shrink thyroid nodules, in a review paper from 2025. Thyroid nodules affect up to sixty percent of adults, ranging from harmless lumps to cancers. Heat shock proteins help cells survive stress and can keep nodules alive.
Compounds like curcumin, resveratrol, and quercetin can tune those guardian proteins. The review traces how they steer cell death, self-cleaning, and stress balance through known signal paths. Lab proof shows they can lower the guardians and push tumor cells toward death. Human use lags, since the compounds absorb poorly and dosing is unsettled.
Catalog record
| CREATOR | Ruina Zhang, Juanqin Lv |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 47 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |