Co-isolation of genetically distinct Burkholderia pseudomallei strains from a single patient in North Queensland
Pauline M. L. Coulon, Piklu Roy Chowdhury, Ian Gassiep, Kay Ramsay, Aven Lee, Edita Ritmejeryte, Miranda E. Pitt, Joyce To, Sarah Reed, Patrick N. A. Harris, Garry S. A. Myers, William C. Nierman, William C. Nierman, William C. Nierman · 2025
Read Co-isolation of genetically distinct Burkholderia pseudomallei strains from a single patient in North Queensland by Pauline M. L. Coulon, Piklu Roy Chowdhury, Ian Gassiep, Kay Ramsay, Aven Lee, Edita Ritmejeryte, Miranda E. Pitt, Joyce To, Sarah Reed, Patrick N. A. Harris, Garry S. A. Myers, William C. Nierman, William C. Nierman, William C. Nierman (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12714287.txt.
Description
Pauline Coulon and co-authors report that one patient's infection held two genetically distinct strains of Burkholderia pseudomallei, the bacterium behind melioidosis. Published in 2025, the case comes from a hospital in Townsville, in North Queensland, Australia, from 2018. The team noticed colony shape differences within isolates from a single infection, and typing showed two separate strains.
Simultaneous infection by more than one strain is rarely documented; earlier reports come from Thailand. The team gives the co-infecting pair a full multi-omics workup, the first of its kind for such a case. They argue the finding should shape how this infection is diagnosed and treated, since one strain's profile may not cover the other.
Catalog record
| CREATOR | Pauline M. L. Coulon, Piklu Roy Chowdhury, Ian Gassiep, Kay Ramsay, Aven Lee, Edita Ritmejeryte, Miranda E. Pitt, Joyce To, Sarah Reed, Patrick N. A. Harris, Garry S. A. Myers, William C. Nierman, William C. Nierman, William C. Nierman |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 79 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |