mRNA vaccine platforms and novel delivery systems: From mechanistic principles to clinical translation
Yunchang Yang, Yunqin Sun, Xinyao Kang, Yaofeng Wang · 2025
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Description
Yunchang Yang, Yunqin Sun, Xinyao Kang, and Yaofeng Wang published a 2025 review of mRNA vaccine design and delivery. Vaccines of this kind teach the body to build one piece of a germ, so the immune system learns to fight the real thing. The COVID-19 shots proved the idea at world scale and sped up work on new forms.
The review explains how the mRNA strand is built and tuned for strength and shelf life. It then surveys carriers that ferry the strand into cells, from fat bubbles to tiny plastic beads and shell-like particles. New uses reach past flu-like illness to cancer and diseases of the immune system itself. Hard problems stay: keeping shots stable, reaching cells well, and making enough for all.
Catalog record
| CREATOR | Yunchang Yang, Yunqin Sun, Xinyao Kang, Yaofeng Wang |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 45 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |