Effectiveness of different antibiotic lock solutions on catheter-related infections of hemodialysis patients: a systematic review and meta-analysis
Sogand Sarmadi, Neda Sanaie, Akbar Zare-Kaseb · 2025
Read Effectiveness of different antibiotic lock solutions on catheter-related infections of hemodialysis patients: a systematic review and meta-analysis by Sogand Sarmadi, Neda Sanaie, Akbar Zare-Kaseb (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12713221.txt.
Description
Sogand Sarmadi, Neda Sanaie, and Akbar Zare-Kaseb published a 2025 pooled review of antibiotic lock therapy for dialysis patients. The therapy fills a patient's tube with a strong drug solution between sessions to keep germs out. The team pooled 17 studies covering 3,482 tubes, and compared drug locks with plain or no-lock care. Trials and near-trial studies both counted.
Drug locks cut blood infections from the tubes by 63 percent, with strong proof behind the result. Overall tube infection rates fell sharply as well. No clear effect appeared for skin entry site infections, clots, or deaths. The authors rate the main result as solid but flag signs of publication bias. They back the therapy as a preventive add-on for dialysis care.
Catalog record
| CREATOR | Sogand Sarmadi, Neda Sanaie, Akbar Zare-Kaseb |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 51 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |