An increase of NPY1 expression leads to inhibitory phosphorylation of PIN-FORMED (PIN) proteins and suppression of pinoid (pid) null mutants
Michael Mudgett, Zhouxin Shen, Ruofan Kang, Xinhua Dai, Steven P Briggs, Yunde Zhao, Detlef Weigel, Michael Mudgett, Zhouxin Shen, Ruofan Kang, Xinhua Dai, Steven P Briggs, Yunde Zhao · 2025
Read An increase of NPY1 expression leads to inhibitory phosphorylation of PIN-FORMED (PIN) proteins and suppression of pinoid (pid) null mutants by Michael Mudgett, Zhouxin Shen, Ruofan Kang, Xinhua Dai, Steven P Briggs, Yunde Zhao, Detlef Weigel, Michael Mudgett, Zhouxin Shen, Ruofan Kang, Xinhua Dai, Steven P Briggs, Yunde Zhao (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12711196.txt.
Description
Michael Mudgett and co-authors untangle how two plant genes steer the hormone flows that let a plant start to flower. Their 2025 study uses Arabidopsis, a small plant that serves as a lab standard. A plant that lacks one gene, called PID, never starts flowers on its stems, and faults in a gene family called NPY give the same blank look.
The team found that boosting the gene NPY1 fully masks the loss of PID, which places NPY1 downstream of it. The boost also switches on tags on the PIN proteins, which move the hormone, at fresh sites that differ from the known ones. Those tags seem to hold the PIN proteins back. A tail part of NPY1 must itself be tagged for the rescue to work.
Catalog record
| CREATOR | Michael Mudgett, Zhouxin Shen, Ruofan Kang, Xinhua Dai, Steven P Briggs, Yunde Zhao, Detlef Weigel, Michael Mudgett, Zhouxin Shen, Ruofan Kang, Xinhua Dai, Steven P Briggs, Yunde Zhao |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 78 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |