Far-infrared irradiation attenuates vessel contraction by activating SERCA2 through disruption of SERCA2 and PLN interaction

Yun-Jin Hwang, So-Young Park, Jung-Hyun Park, Du-Hyong Cho · 2025

Read Far-infrared irradiation attenuates vessel contraction by activating SERCA2 through disruption of SERCA2 and PLN interaction by Yun-Jin Hwang, So-Young Park, Jung-Hyun Park, Du-Hyong Cho (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12711061.txt.

Description

Yun-Jin Hwang and co-authors find how far-infrared light relaxes blood vessels. Their 2025 study uses rat vessel cells and aortas to trace the mechanism behind the gentle dilation long reported for far-infrared therapy.

The light boosted a calcium pump that hauls calcium out of the cell's working fluid into storage, calming contraction. Blocking that pump, or silencing its gene, erased the effect. The trigger was a parting: the rays separated the pump from its natural brake protein without changing either's amount. Mere heat at thirty-nine degrees did none of this. Treated vessels resisted a constricting drug, and blood flow rose in mouse neck arteries. The authors see support for far-infrared therapy against vessel spasm.

Catalog record

CREATORYun-Jin Hwang, So-Young Park, Jung-Hyun Park, Du-Hyong Cho
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE52 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12711061

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