Pre-vaccine immune profiling in cancer patients identifies correlates of COVID-19 vaccine responses
Maryam Kazerani, Simeon Mahov, Joslyn Foley, Noah M Merin, So Yung Choi, Joseph Lownik, Alexander M Xu, Larry Milshteyn, Anton Luis Villamejor, Maimoona Nadri, Nathalie Nguyen, Elham Kazemian, Omid Hamid, Justin Darrah, Jun Gong, Ronald Paquette, Robert Vescio, Inderjit Mehmi, Warren G Tourtellotte, · 2025
Read Pre-vaccine immune profiling in cancer patients identifies correlates of COVID-19 vaccine responses by Maryam Kazerani, Simeon Mahov, Joslyn Foley, Noah M Merin, So Yung Choi, Joseph Lownik, Alexander M Xu, Larry Milshteyn, Anton Luis Villamejor, Maimoona Nadri, Nathalie Nguyen, Elham Kazemian, Omid Hamid, Justin Darrah, Jun Gong, Ronald Paquette, Robert Vescio, Inderjit Mehmi, Warren G Tourtellotte, (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12710909.txt.
Description
Maryam Kazerani and a large team profile immune systems of cancer patients before COVID vaccination. Their study from twenty twenty-five seeks predictors of vaccine response. Cancer treatment weakens responses to messenger RNA vaccines. Knowing who responds poorly could guide extra protection steps.
Sixty-six patients on active treatment gave pre-vaccine blood samples. Mass cytometry catalogued their immune cell types in detail. Antibody levels after vaccination were measured by standard assays. T-cell response breadth was read from receptor sequencing. Certain baseline immune features tracked stronger vaccine answers. Others flagged patients likely to respond weakly. Pre-vaccine profiling could personalise booster timing for cancer patients.
Catalog record
| CREATOR | Maryam Kazerani, Simeon Mahov, Joslyn Foley, Noah M Merin, So Yung Choi, Joseph Lownik, Alexander M Xu, Larry Milshteyn, Anton Luis Villamejor, Maimoona Nadri, Nathalie Nguyen, Elham Kazemian, Omid Hamid, Justin Darrah, Jun Gong, Ronald Paquette, Robert Vescio, Inderjit Mehmi, Warren G Tourtellotte, |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 29 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |