Platelet-to-high-density lipoprotein cholesterol ratio as a potential mediator in the obesity-chronic kidney disease association among hypertensive patients
Xun Huang, Weihua Liu, Qinghua Liu, Lin Huang · 2025
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Description
Xun Huang and co-authors study a blood ratio and kidney disease in this 2025 paper. The ratio compares platelets with HDL, the so-called good cholesterol. Obesity raises the risk of chronic kidney disease, above all in people with high blood pressure. The team asked whether this ratio helps explain that link.
They used survey data from more than ten thousand United States adults with high blood pressure. The ratio's link to kidney disease formed a U shape, rising at both low and high ends. The link was strongest in adults with obesity. The ratio also carried about a fifth of obesity's total effect on kidney risk. It may serve as a cheap risk marker.
Catalog record
| CREATOR | Xun Huang, Weihua Liu, Qinghua Liu, Lin Huang |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 40 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |