Shared donor–recipient γδ T‐cell phenotypic and repertoire features associate with cytomegalovirus reactivation after allogeneic haematopoietic stem cell transplantation

Paula Hahn, Arwen Stikvoort, Faisal Alagrafi, Ahmed Gaballa, Martin Solders, Sofie Vonlanthen, Johan Karlsson Törlén, Lucas C M Arruda, Thomas Poiret, Michael Uhlin · 2025

Read Shared donor–recipient γδ T‐cell phenotypic and repertoire features associate with cytomegalovirus reactivation after allogeneic haematopoietic stem cell transplantation by Paula Hahn, Arwen Stikvoort, Faisal Alagrafi, Ahmed Gaballa, Martin Solders, Sofie Vonlanthen, Johan Karlsson Törlén, Lucas C M Arruda, Thomas Poiret, Michael Uhlin (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12710090.txt.

Description

Paula Hahn and nine co-authors study a rare kind of T cell after stem cell transplants, in a research paper from 2025. The patients had blood cancers, and the transplant is their only chance of cure. The cells in focus mix features of fast, innate defense and slower, targeted defense.

Blood samples came from patients and their donors, before and after transplant. The rare cells kept a steady profile for six months after transplant. One donor cell pattern was linked to a lower risk of a common virus waking up in the patient. Other patterns were linked to that virus returning. The authors say donor cells may help shape this risk.

Catalog record

CREATORPaula Hahn, Arwen Stikvoort, Faisal Alagrafi, Ahmed Gaballa, Martin Solders, Sofie Vonlanthen, Johan Karlsson Törlén, Lucas C M Arruda, Thomas Poiret, Michael Uhlin
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE45 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12710090

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