The radioenhancer NBTXR3: bridging physics and biology to improve radiotherapy outcomes and prime anti-tumor immunity
Célia Bienassis, Omar I Vivar, Yun Hu, Jordan Da silva, Audrey Darmon, Julie Marill, Naeemunnisa Mohamed Anesary, Peter Schmitt, Laurent Levy, James Welsh, Yolanda Prezado, Frédérique Megnin-Chanet, Sébastien Paris · 2025
Read The radioenhancer NBTXR3: bridging physics and biology to improve radiotherapy outcomes and prime anti-tumor immunity by Célia Bienassis, Omar I Vivar, Yun Hu, Jordan Da silva, Audrey Darmon, Julie Marill, Naeemunnisa Mohamed Anesary, Peter Schmitt, Laurent Levy, James Welsh, Yolanda Prezado, Frédérique Megnin-Chanet, Sébastien Paris (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12709859.txt.
Description
Célia Bienassis and colleagues published a review in 2025 on NBTXR3, a nanoparticle treatment designed to make radiotherapy work harder against tumors. Radiotherapy is used in more than half of cancer cases, yet doctors must limit the dose to avoid harming healthy tissue nearby. The review explains how physics and biology meet in this approach.
Injected into a tumor, the nanoparticles amplify the effect of radiation inside the tumor without adding toxicity in surrounding healthy tissue. The authors describe better tumor control in early work and evidence from animal studies that the activated particles can also stir a wider immune response against cancer. Readers get a clear account of why the treatment might improve outcomes and support immunotherapy.
Catalog record
| CREATOR | Célia Bienassis, Omar I Vivar, Yun Hu, Jordan Da silva, Audrey Darmon, Julie Marill, Naeemunnisa Mohamed Anesary, Peter Schmitt, Laurent Levy, James Welsh, Yolanda Prezado, Frédérique Megnin-Chanet, Sébastien Paris |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 41 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |