A combination of ethanol and arachidonic acid promotes steatosis and endoplasmic reticulum stress and impairs mitochondrial respiration in H9c2 cardiomyoblasts
Weilun Ai, Emily New, Carol A. Casey, Viswanathan Saraswathi · 2025
Read A combination of ethanol and arachidonic acid promotes steatosis and endoplasmic reticulum stress and impairs mitochondrial respiration in H9c2 cardiomyoblasts by Weilun Ai, Emily New, Carol A. Casey, Viswanathan Saraswathi (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12709855.txt.
Description
Weilun Ai, Emily New, Carol Casey, and Viswanathan Saraswathi report a 2025 study on how alcohol and a common fat in food may harm heart cells as a pair. The fat is found in meat and in the walls of body cells. Past work showed alcohol raises levels of this fat and its products in heart cells, which may drive harm.
Rats fed alcohol for six weeks had more of the fat in heart tissue and more signs of cell stress. In lab heart cells, the fat plus alcohol built up more fat than alcohol alone. The pair also cut how well the cell power units breathe and make energy. A drug that blocks fat use eased the fat build-up and lifted cell breathing.
Catalog record
| CREATOR | Weilun Ai, Emily New, Carol A. Casey, Viswanathan Saraswathi |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 49 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |