Amino acids metabolism: a potential target for cancer treatment

Shiqi Ren, Xinyi Zhou, Zhen Wang, Kefei Yuan · 2025

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Description

Shiqi Ren and co-authors review amino acid metabolism in 2025 as a target for cancer care. Tumors rewire how they use amino acids, the building blocks of protein, to fuel growth, survival, invasion, and escape from the immune system. These nutrients also shape how immune cells switch on.

The review maps how amino acids feed the cell's central energy cycle and its recycling system. It then surveys attack routes: blocking the enzymes that process amino acids, diet-based plans, and nano-sized delivery systems. The authors aim to ground future trials that starve tumors of what they crave.

Catalog record

CREATORShiqi Ren, Xinyi Zhou, Zhen Wang, Kefei Yuan
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE112 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12709810

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