Colonic Gastrointestinal Stromal Tumors Demonstrate Unique Biological Characteristics: A Retrospective, Propensity Score-Matched Cohort Study Pooling Multicenter and Literature-Derived Individual Patient Data

Zhuo-Fei Li, Guo-Shuai Chen, Han Li, Chen Li, Hao Wu, Ke-Wei Jiang, Ying-Jiang Ye · 2025

Read Colonic Gastrointestinal Stromal Tumors Demonstrate Unique Biological Characteristics: A Retrospective, Propensity Score-Matched Cohort Study Pooling Multicenter and Literature-Derived Individual Patient Data by Zhuo-Fei Li, Guo-Shuai Chen, Han Li, Chen Li, Hao Wu, Ke-Wei Jiang, Ying-Jiang Ye (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12708988.txt.

Description

Zhuo-Fei Li and co-authors study stromal tumors of the colon in a 2025 cohort study. These tumors grow in the gut wall, and the colon form is exceptionally rare. It seems to behave differently from tumors in the stomach, but fair comparisons under similar conditions were lacking.

The team pooled surgical cases from four hospitals with cases drawn from published reports, and matched them to stomach tumor controls. Colon tumors occurred in older patients, were larger, and divided faster. Rates of a key marker were lower. The authors argue that standard risk systems fit this subtype poorly and need adjustment.

Catalog record

CREATORZhuo-Fei Li, Guo-Shuai Chen, Han Li, Chen Li, Hao Wu, Ke-Wei Jiang, Ying-Jiang Ye
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE34 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12708988

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