Metabolomics-driven prediction of antibiotic resistance: a perspective on pre-genetic intervention
Maytham Hussein, Darren J Creek, Mark Baker, Gauri G Rao, Jian Li, Tony Velkov · 2025
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Description
Maytham Hussein and co-authors argue that metabolomics, the study of small molecules in cells, can flag antibiotic resistance before it becomes fixed in genes, in a 2025 perspective piece. Standard tests detect resistance late, after it is already set. Their frame stages resistance growth in three steps: metabolic compensation, sub-lethal adaptation, then genetic fixation. A short pulse test with a targeted panel yields an early risk index.
Catalog record
| CREATOR | Maytham Hussein, Darren J Creek, Mark Baker, Gauri G Rao, Jian Li, Tony Velkov |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 24 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |