Silent cerebral microvascular disease and the longitudinal risk of cognitive decline in atrial fibrillation
Yusuke Kondo, Keitaro Senoo, Miyo Nakano, Yuki Shiko, Yohei Kawasaki, Masahiro Nakano, Takatsugu Kajiyama, Raita Uchiyma, Masato Yamanouchi, Satoru Kobayashi, Yoko Pearce, Toshihiro Saito, Ryo Takemura, Kusano Kengo, Takashi Kurita, Takashi Uno, Yoshio Kobayashi · 2025
Read Silent cerebral microvascular disease and the longitudinal risk of cognitive decline in atrial fibrillation by Yusuke Kondo, Keitaro Senoo, Miyo Nakano, Yuki Shiko, Yohei Kawasaki, Masahiro Nakano, Takatsugu Kajiyama, Raita Uchiyma, Masato Yamanouchi, Satoru Kobayashi, Yoko Pearce, Toshihiro Saito, Ryo Takemura, Kusano Kengo, Takashi Kurita, Takashi Uno, Yoshio Kobayashi (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12708626.txt.
Description
Kondo and co-authors follow patients with atrial fibrillation to see whether silent brain vessel damage predicts fading thinking skills, in a 2025 study. The SKAF study enrolled 313 people aged 60 and up: 213 with the irregular heartbeat and 99 in normal rhythm. It scanned their brains and tested cognition at the start and after two years. The main measure combined silent strokes and tiny bleeds found on imaging.
New silent damage appeared at the same rate in both groups, about 17 percent. Cognition, though, slipped more in the fibrillation group over the two years. The authors conclude the rhythm problem itself, not just visible vessel injury, tracks with decline.
Catalog record
| CREATOR | Yusuke Kondo, Keitaro Senoo, Miyo Nakano, Yuki Shiko, Yohei Kawasaki, Masahiro Nakano, Takatsugu Kajiyama, Raita Uchiyma, Masato Yamanouchi, Satoru Kobayashi, Yoko Pearce, Toshihiro Saito, Ryo Takemura, Kusano Kengo, Takashi Kurita, Takashi Uno, Yoshio Kobayashi |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 32 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |