Endoscopic liquid biopsies of gastric fluid in a large human patient cohort reveal DNA content as a candidate tumor biomarker in gastric cancer
Francine C Cadoná, Thais F Bartelli, Adriane G Pelosof, Claudia Z Sztokfisz, Adriana P Bueno, Luana Batista do Carmo dos Santos, Gabriela P Branco, Gabriel Oliveira dos Santos, Warley A Nunes, Fernanda A Pintor, Laís Lie Senda de Abrantes, Alexandre Defelicibus, Luiz Gonzaga Vaz Coelho, Marcis Leja, · 2025
Read Endoscopic liquid biopsies of gastric fluid in a large human patient cohort reveal DNA content as a candidate tumor biomarker in gastric cancer by Francine C Cadoná, Thais F Bartelli, Adriane G Pelosof, Claudia Z Sztokfisz, Adriana P Bueno, Luana Batista do Carmo dos Santos, Gabriela P Branco, Gabriel Oliveira dos Santos, Warley A Nunes, Fernanda A Pintor, Laís Lie Senda de Abrantes, Alexandre Defelicibus, Luiz Gonzaga Vaz Coelho, Marcis Leja, (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12707811.txt.
Description
Cadona and a large team test stomach fluid DNA as a marker for stomach cancer in twenty twenty-five. Stomach cancer is hard to diagnose and treat around the world. Better markers could help plan surgery and drug treatment. The team collected fluid during routine scope exams of the stomach.
The cohort held more than one thousand patients with varied stomach conditions. DNA levels in the fluid were much higher in cancer patients than in all other groups. Later stage tumors showed higher levels than earlier stage tumors. In a subset, higher DNA levels linked to longer survival without disease progress. Those tumors also held more immune cells. The authors say fluid DNA may aid diagnosis and could carry prognostic value.
Catalog record
| CREATOR | Francine C Cadoná, Thais F Bartelli, Adriane G Pelosof, Claudia Z Sztokfisz, Adriana P Bueno, Luana Batista do Carmo dos Santos, Gabriela P Branco, Gabriel Oliveira dos Santos, Warley A Nunes, Fernanda A Pintor, Laís Lie Senda de Abrantes, Alexandre Defelicibus, Luiz Gonzaga Vaz Coelho, Marcis Leja, |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 54 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |