Cytokine Profile in Women Affected by Chikungunya: Analysis of a Prospective Cohort in Northeastern Brazil
Thalita do Nascimento Silva, Alberto Rubens Siqueira Nogueira Leal, Francisca Kalline de Almeida Barreto, Luís Arthur Brasil Gadelha Farias, Livia Mendes de Almeida, Rafhaella Nogueira Della Guardia Gondim, Marco Antônio de Freitas Clementino, Edson Holanda Teixeira, Moacyr Jesus Barreto de Melo Rêg · 2025
Read Cytokine Profile in Women Affected by Chikungunya: Analysis of a Prospective Cohort in Northeastern Brazil by Thalita do Nascimento Silva, Alberto Rubens Siqueira Nogueira Leal, Francisca Kalline de Almeida Barreto, Luís Arthur Brasil Gadelha Farias, Livia Mendes de Almeida, Rafhaella Nogueira Della Guardia Gondim, Marco Antônio de Freitas Clementino, Edson Holanda Teixeira, Moacyr Jesus Barreto de Melo Rêg (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12707746.txt.
Description
Chikungunya fever, spread by mosquitoes, often leaves joints aching for months, and women bear much of that burden. Thalita Silva and co-authors followed forty women in northeastern Brazil in 2025 from the first days of illness through a full year. Blood drawn at five points tracked the immune signals called cytokines. Ten healthy women served as controls.
More than half the patients still hurt at the later visits. One calming signal, IL-10, stayed raised from the third week onward and differed clearly from day zero at six months and a year. Another signal, IL-18, climbed early. The authors note such shifting profiles may reflect each host's genetic background.
Catalog record
| CREATOR | Thalita do Nascimento Silva, Alberto Rubens Siqueira Nogueira Leal, Francisca Kalline de Almeida Barreto, Luís Arthur Brasil Gadelha Farias, Livia Mendes de Almeida, Rafhaella Nogueira Della Guardia Gondim, Marco Antônio de Freitas Clementino, Edson Holanda Teixeira, Moacyr Jesus Barreto de Melo Rêg |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 36 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |