Development of Machine‐Assisted, Human‐Centred Bone Marrow Cell Classification: Feasibility Analysis in Patients With Myelodysplastic Syndromes

Kiyoyuki Ogata, Yuto Mochimaru, Leonie Saft, Gerrit Sijm, Bouchra Badaoui, Canan Alhan, Carole Almire, Yosuke Kato, Daisuke Sakamoto, Naoko Chiba, Naho Murata, Nana Kasai, Kazuma Sei, Naoya Kawahara, Mika Ogata, Nicolas Chapuis, Orianne Wagner‐Ballon, Arjan van de Loosdrecht, Yumi Yamamoto · 2025

Read Development of Machine‐Assisted, Human‐Centred Bone Marrow Cell Classification: Feasibility Analysis in Patients With Myelodysplastic Syndromes by Kiyoyuki Ogata, Yuto Mochimaru, Leonie Saft, Gerrit Sijm, Bouchra Badaoui, Canan Alhan, Carole Almire, Yosuke Kato, Daisuke Sakamoto, Naoko Chiba, Naho Murata, Nana Kasai, Kazuma Sei, Naoya Kawahara, Mika Ogata, Nicolas Chapuis, Orianne Wagner‐Ballon, Arjan van de Loosdrecht, Yumi Yamamoto (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12707303.txt.

Description

Kiyoyuki Ogata and co-authors build a machine-assisted method to classify bone marrow cells in this 2025 study. Experts sort marrow cells by eye under a microscope to diagnose blood diseases. That work takes skill and time and can vary between observers.

Their system captures single cell images with a blood cell analyzer, then shows them on a large screen for expert calls. Over three and a half years, most aspirated samples were handled this way. Images at high magnification are stored for good, so anyone can recheck them later. Side-by-side views across cell classes sharpen accuracy. Blast counts matched standard microscopy in marrow syndrome cases.

Catalog record

CREATORKiyoyuki Ogata, Yuto Mochimaru, Leonie Saft, Gerrit Sijm, Bouchra Badaoui, Canan Alhan, Carole Almire, Yosuke Kato, Daisuke Sakamoto, Naoko Chiba, Naho Murata, Nana Kasai, Kazuma Sei, Naoya Kawahara, Mika Ogata, Nicolas Chapuis, Orianne Wagner‐Ballon, Arjan van de Loosdrecht, Yumi Yamamoto
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE32 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12707303

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