Clinical Characteristics of Granular Parakeratosis Caused by Benzalkonium Chloride: A Retrospective Case Series
Fan Lin, Yingwei Wang, Shisheng Chen · 2025
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Description
A rare skin disorder, granular parakeratosis, has lately been traced in some patients to benzalkonium chloride, a disinfectant found in many household products. Lin, Wang, and Chen gather eight such cases from one clinic to describe the pattern.
The patients, six of them male and four of them children, developed red-brown patches with a distinctive parchment-like scale, mostly in the groin, trunk, and neck. Under the microscope every case showed the telltale retained granules in the skin's outer layer. Once the chemical exposure stopped and simple moisturizers were used, every patient's skin cleared within two weeks to a month. The authors highlight the parchment scale as a diagnostic clue and suspect children may be especially vulnerable to this irritant.
Catalog record
| CREATOR | Fan Lin, Yingwei Wang, Shisheng Chen |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 21 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |