Sleep disorders in Parkinson’s disease: evaluating pharmacological treatments through systematic review and meta-analysis
Jingqi Li, Runtang Zhou, Jialin Deng, Hong Zhou, Jun Hu, Xinzheng Wang · 2025
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Description
Jingqi Li and co-authors pool trial evidence on drugs for sleep troubles in Parkinson's disease. Their 2025 meta-analysis covers 23 randomized trials. Sleep problems are the commonest non-motor burden in the disease, yet drug guidance has stayed unsettled.
Drugs clearly helped daytime sleepiness and insomnia on pooled scores. They did not beat controls for the acting-out dream disorder that hits many patients. Evidence quality ranged from very low to moderate across the set. Trials split by problem type: seven each for the dream disorder and sleepiness, six for insomnia. The authors ask for stronger trials on the dream disorder most of all.
Catalog record
| CREATOR | Jingqi Li, Runtang Zhou, Jialin Deng, Hong Zhou, Jun Hu, Xinzheng Wang |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 46 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |