Development of a nomogram for predicting the long-term risk of hepatocellular carcinoma after antiviral treatment for hepatitis C

Jing Li, Baima Yangjin, Chengbin Zhu, Weicheng Xu, Yingli He · 2025

Read Development of a nomogram for predicting the long-term risk of hepatocellular carcinoma after antiviral treatment for hepatitis C by Jing Li, Baima Yangjin, Chengbin Zhu, Weicheng Xu, Yingli He (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12706893.txt.

Description

Jing Li and co-authors build a chart to estimate liver cancer risk after hepatitis C is cured, in this 2025 study. Modern antiviral drugs clear the virus in most patients, a state called sustained response. Whether the newer drugs change later cancer risk, compared with older interferon treatment, has stayed in dispute. Even after cure, some risk remains, so follow-up cannot simply stop.

The team followed more than four hundred treated patients and matched two hundred of them into fair comparison groups. Statistical sieves picked the traits tied to later cancer on their own. Those traits feed a nomogram, a chart that turns a patient's values into a personal risk estimate. Such a chart can tell doctors which cured patients still need close liver checks and which can be watched less often.

Catalog record

CREATORJing Li, Baima Yangjin, Chengbin Zhu, Weicheng Xu, Yingli He
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE34 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12706893

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