Comparative effectiveness of adjunctive rifampicin versus gentamicin for prosthetic valve endocarditis due to Staphylococcus aureus
Taito Kitano, Sayaka Yoshida · 2025
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Description
Taito Kitano and Sayaka Yoshida compare two added antibiotics for staph infection of an artificial heart valve in 2025. Guidelines have backed adding rifampicin or gentamicin, but hard data on which works better are thin.
Using a large records network from US centers, the authors matched patients who got one drug but not the other. Death within one year was lower in the rifampicin group than in the gentamicin group. Other outcomes, such as return of infection or kidney failure, did not differ clearly. The authors urge caution, since records can hide key details such as treatment length.
Catalog record
| CREATOR | Taito Kitano, Sayaka Yoshida |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 28 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |