Volumetric MRI and FDG-PET hypometabolism biomarkers of frontotemporal dementia: protocol for a systematic review and meta-analysis

Taylor J Solomon, Ana Antonic-Baker, Lorena Romero, Benjamin Sinclair, Terence J O’Brien, Lucy Vivash · 2025

Read Volumetric MRI and FDG-PET hypometabolism biomarkers of frontotemporal dementia: protocol for a systematic review and meta-analysis by Taylor J Solomon, Ana Antonic-Baker, Lorena Romero, Benjamin Sinclair, Terence J O’Brien, Lucy Vivash (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12706253.txt.

Description

Taylor J Solomon and co-authors set out a plan for a review of brain scan markers in frontotemporal dementia, in a 2025 protocol paper. The disease is hard to diagnose because symptoms, gene faults, and brain changes vary a lot. No single test can yet confirm the type or stage with confidence.

The planned review will pool studies that use scans of brain volume and scans of sugar use in the brain. It asks whether scan patterns can split patients from healthy people, split inherited from non-inherited cases, and split the two main protein types behind the disease. Searches will cover three major databases, with two reviewers screening each study. The protocol is registered, and results will be shared in a peer-reviewed journal.

Catalog record

CREATORTaylor J Solomon, Ana Antonic-Baker, Lorena Romero, Benjamin Sinclair, Terence J O’Brien, Lucy Vivash
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE33 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12706253

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