Adjunctive bright light therapy to enhance continuous positive airway pressure adherence in patients with comorbid major depressive disorder and obstructive sleep apnoea syndrome: study protocol for a randomised sham-controlled trial

Houda El Azzaoui, Sébastien Catoire, Harold Lecharpentier, Juliette Felician, Olivier Grasset, Claude Gronfier, William Vallet, Thierry D’amato, Jérôme Brunelin · 2025

Read Adjunctive bright light therapy to enhance continuous positive airway pressure adherence in patients with comorbid major depressive disorder and obstructive sleep apnoea syndrome: study protocol for a randomised sham-controlled trial by Houda El Azzaoui, Sébastien Catoire, Harold Lecharpentier, Juliette Felician, Olivier Grasset, Claude Gronfier, William Vallet, Thierry D’amato, Jérôme Brunelin (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12706203.txt.

Description

Depression and sleep apnoea travel together in about half of cases, and the breathing mask that treats apnoea only helps if patients actually wear it. Houda El Azzaoui and co-authors lay out the protocol for a trial testing whether morning bright light improves mask adherence. Light therapy is known to lift mood and sharpen sleep and alertness in depression, which might carry patients through the fragile first weeks of mask use.

One hundred thirty patients will get either real bright light or a dim sham light for half an hour daily across their first two weeks on the mask. The main measure is hours of mask use per day; mood, anxiety, and sleep measures follow, with a check one month later. The protocol paper records approvals and registration before results exist.

Catalog record

CREATORHouda El Azzaoui, Sébastien Catoire, Harold Lecharpentier, Juliette Felician, Olivier Grasset, Claude Gronfier, William Vallet, Thierry D’amato, Jérôme Brunelin
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE44 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12706203

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