Intranasal Mosaic H1N1 Live Attenuated Influenza Vaccine Elicits Broad Cross‐Reactive Immunity and Protection Against Group 1 and 2 Influenza A Viruses
Ximeng Ma, Qi Chen, Yukun Cai, Chen Chen, Jian Lu, Zhuolin Yang, Xue Han, Liangliang Wang, Xuejie Liu, Yuhang Shi, Yuhang Zhang, Li Xin, Yihao Chen, Run Ma, Wantong Pang, Tian Bai, Yuelong Shu · 2025
Read Intranasal Mosaic H1N1 Live Attenuated Influenza Vaccine Elicits Broad Cross‐Reactive Immunity and Protection Against Group 1 and 2 Influenza A Viruses by Ximeng Ma, Qi Chen, Yukun Cai, Chen Chen, Jian Lu, Zhuolin Yang, Xue Han, Liangliang Wang, Xuejie Liu, Yuhang Shi, Yuhang Zhang, Li Xin, Yihao Chen, Run Ma, Wantong Pang, Tian Bai, Yuelong Shu (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12706173.txt.
Description
Ximeng Ma and a large team build a broad flu vaccine in a 2025 study. Flu kills near half a million people a year across the world. Weak, live vaccines can wake mouth and nose guards, yet their shield still runs low, so the team sought a stronger build.
Their nose vaccine blends bits of two flu surface parts, picked to hold most of the spots immune cells hunt. The blend rides on a tamed donor strain for safety. Tests in animals showed wide cross-guard against both flu A groups. The build may seed a near-universal flu shot.
Catalog record
| CREATOR | Ximeng Ma, Qi Chen, Yukun Cai, Chen Chen, Jian Lu, Zhuolin Yang, Xue Han, Liangliang Wang, Xuejie Liu, Yuhang Shi, Yuhang Zhang, Li Xin, Yihao Chen, Run Ma, Wantong Pang, Tian Bai, Yuelong Shu |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 80 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |