Peri-appendiceal inflammation is associated with appendiceal orifice stenosis and appendiceal body thickening in ulcerative colitis: A case–control study
Ting Yi, Zejun Song, Hongliang Zhao, Xiaojuan Guo, Yuan Tian, Shiming Zhou, Qing Huang, Bo Jiang, Ruifeng Wang, Yutang Ren · 2025
Read Peri-appendiceal inflammation is associated with appendiceal orifice stenosis and appendiceal body thickening in ulcerative colitis: A case–control study by Ting Yi, Zejun Song, Hongliang Zhao, Xiaojuan Guo, Yuan Tian, Shiming Zhou, Qing Huang, Bo Jiang, Ruifeng Wang, Yutang Ren (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12705978.txt.
Description
In ulcerative colitis, inflammation sometimes gathers around the appendix opening even when the rest of the colon looks calm. Ting Yi and co-authors asked whether that local swelling tracks with structural changes in the appendix itself. They reviewed 169 patients with the disease, scoring inflammation near the appendix during colonoscopy and measuring the appendix on CT scans where available.
About 17 percent of patients had a narrowed or vanished appendix opening, and the odds rose with age and with stronger nearby inflammation. Among the 42 patients scanned, 69 percent had a thickened appendix body, yet none showed signs of ordinary appendicitis. Appendix width also rose with the local score. The authors suggest the inflammation grade near the appendix can serve as an indirect sign of appendix involvement in this disease.
Catalog record
| CREATOR | Ting Yi, Zejun Song, Hongliang Zhao, Xiaojuan Guo, Yuan Tian, Shiming Zhou, Qing Huang, Bo Jiang, Ruifeng Wang, Yutang Ren |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 25 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |