Population-scale gene expression analysis reveals the contribution of expression diversity to the modern wheat improvement
Zhimeng Zhang, Shengwei Ma, Mou Yin, Caihong Zhao, Xinyu Zhao, Yang Yu, Haojie Wang, Xuanzhao Li, Yaoqi Si, Jianqing Niu, Jingzhong Xie, Limin Wang, Jiajie Wu, Yanming Zhang, Qi Zheng, Shusong Zheng, Ni Jiang, Xigang Liu, Hong-Qing Ling, Fei He · 2025
Read Population-scale gene expression analysis reveals the contribution of expression diversity to the modern wheat improvement by Zhimeng Zhang, Shengwei Ma, Mou Yin, Caihong Zhao, Xinyu Zhao, Yang Yu, Haojie Wang, Xuanzhao Li, Yaoqi Si, Jianqing Niu, Jingzhong Xie, Limin Wang, Jiajie Wu, Yanming Zhang, Qi Zheng, Shusong Zheng, Ni Jiang, Xigang Liu, Hong-Qing Ling, Fei He (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12705824.txt.
Description
Zhimeng Zhang, Fei He, and a large team of colleagues read gene activity across 328 wheat lines, from old landraces to modern elite types bred in China and the United States. Most work on crop traits looks at DNA letters alone. Gene activity varies just as much, and a single reference genome misses genes that some lines carry and others lack.
Using a pan-genome, the team found over twenty-three thousand transcripts the standard reference had missed. They built a map of the DNA spots that tune each gene's activity. That map yielded 299 strong candidate genes for 34 farm traits and for resistance to eight mildew strains. Tests in a mutant library backed most of them. The work shows breeding has reshaped gene activity, not just gene content.
Catalog record
| CREATOR | Zhimeng Zhang, Shengwei Ma, Mou Yin, Caihong Zhao, Xinyu Zhao, Yang Yu, Haojie Wang, Xuanzhao Li, Yaoqi Si, Jianqing Niu, Jingzhong Xie, Limin Wang, Jiajie Wu, Yanming Zhang, Qi Zheng, Shusong Zheng, Ni Jiang, Xigang Liu, Hong-Qing Ling, Fei He |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 104 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |