Efficacy and safety of home-based transcranial direct current stimulation (tDCS) on patients with depressive disorders: a systematic review and meta-analysis of randomized clinical trials
Reza Moshfeghinia, Sanaz Bordbar, Yasamin Roointanpour, Melika Arab Bafrani, Mohammadreza Shalbafan · 2025
Read Efficacy and safety of home-based transcranial direct current stimulation (tDCS) on patients with depressive disorders: a systematic review and meta-analysis of randomized clinical trials by Reza Moshfeghinia, Sanaz Bordbar, Yasamin Roointanpour, Melika Arab Bafrani, Mohammadreza Shalbafan (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12705823.txt.
Description
Reza Moshfeghinia and his four co-authors pool, in a 2025 review, the trial evidence for treating depression with gentle electric stimulation used at home. The technique passes a weak current through the scalp to nudge brain activity. Clinic versions exist; home versions promise reach and convenience. From over 500 studies, five randomized trials with 415 patients met the bar.
Active stimulation beat sham treatment on both standard depression scales, by roughly two to three points, and eased anxiety scores as well. Reported side effects were mild and local: skin redness, tingling or burning, and occasional headaches. The authors judge home treatment effective on current evidence. They call for bigger trials with better adherence tracking and long-term follow-up before it can be recommended broadly.
Catalog record
| CREATOR | Reza Moshfeghinia, Sanaz Bordbar, Yasamin Roointanpour, Melika Arab Bafrani, Mohammadreza Shalbafan |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 32 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |