Inhalable nanoparticle-based drug delivery system for non-small cell lung cancer therapy: promises and challenges

Molham Sakkal, Ranim W. A. Abdelmoteleb, Aya Al Ali, Yousef A. Bin Jardan, Raimar Löbenberg, Muhammad Sarfraz · 2025

Read Inhalable nanoparticle-based drug delivery system for non-small cell lung cancer therapy: promises and challenges by Molham Sakkal, Ranim W. A. Abdelmoteleb, Aya Al Ali, Yousef A. Bin Jardan, Raimar Löbenberg, Muhammad Sarfraz (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12705525.txt.

Description

Molham Sakkal and co-workers review inhalable nanoparticle delivery for non-small cell lung cancer, in a 2025 paper. This cancer type causes most lung cancer deaths, and standard treatments often fail in advanced stages. Breathing the drug in sends it straight to the lungs and limits body-wide side effects.

Nanoparticles can improve drug stability, protect it from early breakdown, and carry it to tumor cells through surface targeting. The review covers formulations, inhaler devices, and the particle traits that matter for lung delivery. It weighs passive and active targeting and the hurdles that remain. Recent material advances are highlighted as the path forward.

Catalog record

CREATORMolham Sakkal, Ranim W. A. Abdelmoteleb, Aya Al Ali, Yousef A. Bin Jardan, Raimar Löbenberg, Muhammad Sarfraz
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE94 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12705525

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